A potent drug for glioblastoma can't be used in patients. It can't reach its target because it's blocked by the blood-brain barrier, and the conventional formulation for this drug is toxic to the brain. But now scientists have used a novel technology for opening the blood-brain barrier with an implantable ultrasound, and delivered the powerful drug to the tumor in mice. Scientists also identified why drug is toxic and tested a new formulation not harmful to the brain.