Some of our most pressing “ diseases of despair, ” such as addiction and chronic pain, disrupt the brain ’ s capacity to experience healthy pleasure and extract meaning from naturally rewarding events and experiences. For example, prolonged opioid use in the context of chronic pain and distress can blunt positive emotions and compel opioid misuse as a way to hold on to a shrinking sense of well-being.In the first talk of the spring 2021 Integrative Medicine Research Lecture Series presented by the National Center for Complementary and Integrative Health, Dr. Eric Garland of the University of Utah will describe the development and testing of an integrative nondrug treatment strategy, Mindfulness-Oriented Recovery Enhancement (MORE). This approach unites traditional mindfulness meditat...