In the fleeting moments after a liquid is subjected to a sudden change in pressure, microscopic bubbles rapidly form and collapse in a process known as cavitation. In the human brain, this is believed to be a mechanistic cause of traumatic brain injury, or TBI, but the phenomenon has yet to be directly observed in brain tissue because the bubbles appear and disappear within microseconds. To address this, researchers are seeking to understand how cavitation might injure neurons by using a 3-D imaging system coupled with a diffraction grating to examine their post-exposure morphology.