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Disproving hypothesis clears path for research for new treatment options for schizophrenia

Researchers reported results from the first repeated-dose study of a dopamine-1 receptor (D1R) agonist for treating the cognitive and negative symptoms of schizophrenia yesterday in the Journal of…

Study shows genetic counseling helps psychiatric patients

A new University of British Columbia study shows that genetic counselling helps patients with schizophrenia, bipolar disorder and similar conditions understand and cope with their illness.

"Schizophrenia" does not exist, argues expert

The term “schizophrenia,” with its connotation of hopeless chronic brain disease, should be dropped and replaced with something like “psychosis spectrum syndrome,” argues a professor of psychiatry…

Genetic study provides first-ever insight into biological origin of schizophrenia

A landmark study, based on genetic analysis of nearly 65,000 people, has revealed that a person’s risk of schizophrenia is increased if they inherit specific variants in a gene related to “synaptic…

Computer modeling provides insight into cellular-level effects of schizophrenia risk genes

Numerous genetic variants associated with risk for schizophrenia have been identified. However, little is known about how these genes have their effects in the brain.

New schizophrenia treatments may be effective for subgroup of patients

Mounting evidence indicates that disturbances in the brain’s glutamate pathway contribute to symptoms of schizophrenia.

UTSW-led study establishes biomarkers to help diagnose, treat psychosis

In a groundbreaking study led by UT Southwestern Medical Center, a comprehensive set of empirical biomarkers has been established to aid in diagnosis and treatment of psychosis.

Scientists discover link between loss of grey matter and negative schizophrenia symptoms

New research published online today in the British Journal of Psychiatry, suggests an association between the loss of brain grey matter tissue and the development of negative symptoms in people…

Neurological underpinnings of schizophrenia just as complex as the disorder itself

New analysis links cognitive, emotional, and intellectual symptoms to neurological ‘disruption’ in multiple brain regions – a finding with important implications for diagnosis and treatment.

Better options for people with treatment-resistant schizophrenia

Research on the comparative effectiveness of antipsychotic medications.In real-world settings, patients with schizophrenia whose symptoms do not respond to standard antipsychotic medications have…