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Largest study of its kind finds rare genetic variations linked to schizophrenia

Many of the genetic variations that increase risk for schizophrenia are rare, making it difficult to study their role in the disease.

Schizophrenia risk increased with alcohol, drug abuse

The links between schizophrenia and drug abuse are a hotly debated topic. A new Danish study casts their net wide and gleams new insight.

Study shows low vitamin D levels are associated with increased negative and depressive symptoms in psychotic disorders

New research presented at this year’s International Early Psychosis Association (IEPA) meeting in Milan, Italy (20-22 October) shows that low vitamin D status is associated with increased negative…

In search of neurobiological factors for schizophrenia

It is impossible to predict the onset of schizophrenic psychosis. If factors linked to a risk of psychosis can be identified, however, these may yield significant insights into its underlying…

Clozapine shows better efficacy in children with schizophrenia than in adults

Childhood-onset schizophrenia is a rare, severe, and difficult to treat form of the disease, but a new study suggests that children show a stronger response to clozapine than to other antipsychotic…

Genetic data uncovers multiple facets of schizophrenia

Four different genetic mutations appear to account for four distinct forms of schizophrenia. This could mean more targeted therapy options for 1 in 3 patients with the condition.

For young people with schizophrenia, physical and mental exercises offer hope

Workouts appear to trigger ‘Miracle-Gro for the brain’ that restores connections between neurons, UCLA researchers find.

Risk allele for side effects induced by Clozapine identified

Clozapine (CLZ) is a “gold standard” drug for managing treatment-resistant schizophrenia (TRS), who do not respond adequately to first-line antipsychotics.

Molecular mechanism for higher brain functions and neuropsychiatric disorders

Implications for the development of new treatment strategies for neuropsychiatric disorders.

New studies of the ‘natural history’ of schizophrenia raise hope for new treatments

Emerging evidence on the development, “prodromal” characteristics, and long-term course of schizophrenia provide reasons for optimism for developing new treatments and preventive approaches for…