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Electroconvulsive therapy (ECT) is the most acutely effective treatment for severe, sometimes life-threatening, depression.

Animal brain study shows noradrenaline neurons in the locus coeruleus regulate stress susceptibility and resilience by influencing dopamine neurons in the ventral tegmental area.

A virtual reality scenario has helped patients with depressive symptoms to feel more compassionate toward themselves, offering promise for a future therapy.

Doctors should discuss treatment effects, adverse effect profiles, costs, accessibility, and preferences with patients when selecting a first line treatment.

The ACP compared the effectiveness cognitive behavioral therapy and antidepressants for major depression, finding that the two treatments are just as beneficial.

Depression can be a devastating and unremitting problem.Researchers of a new study published in the current issue of Biological Psychiatry report successful reduction of depressive symptoms in…

Growing up with parents who are depressed can have a negative impact on school grades for children up to the age of 16 years, but intervention could help to mitigate the effects.

Allergan plc., a leading global pharmaceutical company has announced that its Phase III ready investigational medication rapastinel (GLYX-13) received Breakthrough Therapy designation from the U.S.

Serious risks of common antidepressant medications prescribed for children have been underplayed by drug companies, increasing the danger of suicide and aggression.

Depression is more likely to be inherited from mothers to daughters than from mothers to sons or fathers to either gender, says MRI-based research into brain structures.