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High status job means you are less likely to respond to treatment for depression

An international study has found that having a high status job means that you are less likely to respond to standard treatment with medications for depression.

Esketamine produces rapid effects in treatment-resistant depression

A new study in Biological Psychiatry reports that esketamine, a component of the general anesthetic ketamine, shows rapid and significant improvement in depressive symptoms in patients who do not…

Study examines risk, risk factors for depression after stroke

During the first three months after stroke, the risk for depression was eight times higher than in a reference population of people without stroke, according to an article published online by JAMA…

Understanding the unhappy side of serotonin

Antidepressants improve mood by boosting serotonin levels, but serotonin can have negative effects, too. Scientists have been exploring why this happens.

Chronic pain more common in partners of depressed individuals

Chronic pain and depression are both common and mysterious conditions. New research looks at the mix of environmental and genetic factors behind them.

Mindfulness combats depression for disadvantaged black women

Participants learn to handle daily stresses and gain more control through yoga, breathing, body scans.

Correcting metabolic deficiencies may improve depression symptoms

Identifying and treating metabolic deficiencies in patients with treatment-resistant depression can improve symptoms and in some cases even lead to remission, according to new research from the…

Depression screening tools not accurate for children and adolescents

A common way for doctors to try and identify depression in children and adolescents is by using short questionnaires.

Genetic associations for major depressive disorder

The discovery of 15 regions of the genome associated with major depressive disorder (MDD) in individuals of European descent is reported in a study published online this week in Nature Genetics.

Depression: 15 genomic regions linked with diagnosis

Researchers have located 15 genomic regions that are associated with depression. Several of these sites are near genes involved in brain development.