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A fragment of human brain, mapped in exquisite detail

Researchers have created the largest synaptic-resolution, 3D reconstruction of a piece of human brain to date, showing in vivid detail each cell and its web of neural connections in a piece of human temporal cortex about half the size of a rice grain.

High school student helps transform ‘crazy idea’ into innovative research tool

A ‘crazy idea’ hatched during a walk in the woods and first tested by a high school student is now an innovative research tool used by scientists worldwide to predict neurotransmitters in fruit fly connectomes.

Study shows heightened sensitivity to PTSD in autism

A new study shows that a mild stress is enough to trigger post-traumatic stress disorder (PTSD) in mouse models of autism spectrum disorder (ASD). Researchers demonstrated that the two disorders share a reciprocal relationship, identifying a predisposi…

Brain mechanisms underlying sensory hypersensitivity in a mouse model of autism spectrum disorder

A research team has identified the primary cause of sensory hypersensitivity in a mouse model of autism spectrum disorders (ASD).

‘Wraparound’ implants represent new approach to treating spinal cord injuries

A tiny, flexible electronic device that wraps around the spinal cord could represent a new approach to the treatment of spinal injuries, which can cause profound disability and paralysis. A team of engineers, neuroscientists and surgeons developed the …

Childhood maltreatment responsible for up to 40 percent of mental health conditions

A study has found the widespread impact of child abuse and neglect, with analysis suggesting they cause nearly half of common mental conditions. Researchers say childhood maltreatment should be treated as a public health priority.

How psychedelic drugs interact with serotonin receptors to potentially produce therapeutic benefits

Researchers have shed valuable light on the complex mechanisms by which a class of psychedelic drugs binds to and activates serotonin receptors to produce potential therapeutic effects in patients with neuropsychiatric disorders such as depression and …

‘Mathematical microscope’ reveals novel, energy-efficient mechanism of working memory that works even during sleep

Researchers have discovered a mechanism that creates memories while reducing metabolic cost, even during sleep. This efficient memory occurs in a part of the brain that is crucial for learning and memory, and where Alzheimer’s disease begins.

Genetics, not lack of oxygen, causes cerebral palsy in quarter of cases

The world’s largest study of cerebral palsy (CP) genetics has discovered genetic defects are most likely responsible for more than a quarter of cases in Chinese children, rather than a lack of oxygen at birth as previously thought.

Breakthrough paves the way for next generation of vision implants

A group of researchers have created an exceptionally small implant, with electrodes the size of a single neuron that can also remain intact in the body over time — a unique combination that holds promise for future vision implants for the blind.