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Sequencing of the developing human brain uncovers hundreds of thousands of new gene transcripts

Researchers uncovered 214,516 unique isoforms in the developing neocortex — over 70% of which have not been previously studied.

Scientists map networks regulating gene function in the human brain

A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders. These maps detail the many regulatory elements that coordinate the brain…

Psychedelic drug-induced hyperconnectivity in the brain helps clarify altered subjective experiences

A new study shows that the use of psilocybin, a compound found in the widely known ‘magic mushrooms,’ initiates a pattern of hyperconnectivity in the brain linked to the ego-modifying effects and feelings of oceanic boundlessness. The findings help exp…

Study explains why the brain can robustly recognize images, even without color

New research offers a possible explanation for how the brain learns to identify both color and black-and-white images. The researchers found evidence that early in life, when the retina is unable to process color information, the brain learns to distin…

Researchers unveil shared and unique brain molecular dysregulations in PTSD and depression

Researchers analyzed multi-omic data from 231 people with PTSD or depression to uncover distinct molecular differences that might affect systems such as the nervous and immune systems, to contribute to these mental health conditions.

Study uncovers cell type-specific genetic insights underlying schizophrenia

New research provides a map for how the genes known to increase risk of schizophrenia affect specific cells within the brain — information researchers hope can drive the development of new, effective treatments.

Tracking the cellular and genetic roots of neuropsychiatric disease

A new analysis has revealed detailed information about genetic variation in brain cells that could open new avenues for the targeted treatment of diseases such as schizophrenia and Alzheimer’s disease.

Key differences in brain development between autistic boys and girls

A new study finds key differences in the development of the cortex between autistic boys and girls ages 2-13. The study found sex-specific changes in the thickness of the outer layer of the brain, called the cortex.

Wearable ultrasound patch enables continuous, non-invasive monitoring of cerebral blood flow

Engineers have developed a wearable ultrasound patch that can offer continuous, non-invasive monitoring of blood flow in the brain. The soft and stretchy patch can be comfortably worn on the temple to provide three-dimensional data on cerebral blood fl…

Scientists uncover new molecular drivers of Alzheimer’s

At least 5.8 million Americans are currently living with Alzheimer’s disease, which is the most common form of dementia. There is no cure for Alzheimer’s, in part because scientists do not yet have a full understanding of what causes the disease. But a…