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Researchers map individual brain dynamics

Neuroscientists have set up computer frameworks that can help model individual brain dynamics.

Brains of people with sickle cell disease appear older

A new study has found older-looking brains in adults with sickle cell disease, helping to explain the cognitive challenges experienced by such individuals. A brain image from a healthy individual (left) shows a larger brain with more white matter compa…

‘Ding-dong:’ A study finds specific neurons with an immune doorbell

Neuroscientists have identified that the receptor IL-1R1 plays a critical role in enabling neurons to directly communicate with the immune system. The new study provides the most detailed mapping of neuronal IL-1R1 (nIL-1R1) expression in the mouse bra…

Brain changes in Huntington’s disease decades before diagnosis will guide future prevention trials

Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington’s disease, finds a new study.

Aerobic exercise: A powerful ally in fight against Alzheimer’s

Regular aerobic exercise could significantly reduce disease markers associated with Alzheimer’s, new research has found. The findings provide new hope in the battle against this devastating disorder.

HKU study shows ruminating about being lonely is more closely linked to depression than actual loneliness

Past studies have identified a loneliness-rumination-depression nexus. Rumination is defined as repetitive and intrusive negative thoughts and feelings, and loneliness as a gap between desired and actual social connections. Given a widely reported high…

Memory systems in the brain drive food cravings that could influence body weight

A research team identified the brain’s food-specific memory system and its direct role in overeating and diet-induced obesity. They found a specific population of neurons in the mouse brain that encode memories for sugar and fat, profoundly impacting f…

A molecule is shown to produce cognitive improvement in rodents with early Alzheimer’s disease

Scientists have come up with a drug that is a potential candidate for tackling memory deficits in the early stages of the disease in rodents. Research shows that the drug activates the cannabinoid neurotransmitter system (which protects the brain), and…

Researchers identify three psychological profiles that could determine the evolution of mental, cognitive and brain health in aging

An international study has identified three psychological profiles associated with different patterns of cognitive and brain decline in aging. The study, which analyzed more than 1,000 middle-aged and older adults, shows that the specific psychological…

How one brain circuit encodes memories of both places and events

A computational model explains how place cells in the hippocampus can be recruited to form any kind of episodic memory, even when there’s no spatial component.