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Study reveals patients with brain injuries who died after withdrawal of life support may have recovered

Analysis of 1,392 patients with traumatic brain injuries (TBIs) found that some patients for whom life support was withdrawn may have survived and recovered some level of independence a few months after injury. Families are often asked to make decision…

How the brain is flexible enough for a complex world (without being thrown into chaos)

Many neurons exhibit ‘mixed selectivity,’ meaning they can integrate multiple inputs and participate in multiple computations. Mechanisms such as oscillations and neuromodulators recruit their participation and tune them to focus on the relevant inform…

A fragment of human brain, mapped in exquisite detail

Researchers have created the largest synaptic-resolution, 3D reconstruction of a piece of human brain to date, showing in vivid detail each cell and its web of neural connections in a piece of human temporal cortex about half the size of a rice grain.

High school student helps transform ‘crazy idea’ into innovative research tool

A ‘crazy idea’ hatched during a walk in the woods and first tested by a high school student is now an innovative research tool used by scientists worldwide to predict neurotransmitters in fruit fly connectomes.

Study shows heightened sensitivity to PTSD in autism

A new study shows that a mild stress is enough to trigger post-traumatic stress disorder (PTSD) in mouse models of autism spectrum disorder (ASD). Researchers demonstrated that the two disorders share a reciprocal relationship, identifying a predisposi…

Brain mechanisms underlying sensory hypersensitivity in a mouse model of autism spectrum disorder

A research team has identified the primary cause of sensory hypersensitivity in a mouse model of autism spectrum disorders (ASD).

‘Wraparound’ implants represent new approach to treating spinal cord injuries

A tiny, flexible electronic device that wraps around the spinal cord could represent a new approach to the treatment of spinal injuries, which can cause profound disability and paralysis. A team of engineers, neuroscientists and surgeons developed the …

Childhood maltreatment responsible for up to 40 percent of mental health conditions

A study has found the widespread impact of child abuse and neglect, with analysis suggesting they cause nearly half of common mental conditions. Researchers say childhood maltreatment should be treated as a public health priority.

How psychedelic drugs interact with serotonin receptors to potentially produce therapeutic benefits

Researchers have shed valuable light on the complex mechanisms by which a class of psychedelic drugs binds to and activates serotonin receptors to produce potential therapeutic effects in patients with neuropsychiatric disorders such as depression and …

‘Mathematical microscope’ reveals novel, energy-efficient mechanism of working memory that works even during sleep

Researchers have discovered a mechanism that creates memories while reducing metabolic cost, even during sleep. This efficient memory occurs in a part of the brain that is crucial for learning and memory, and where Alzheimer’s disease begins.