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Scientists uncover rapid-acting, low-side-effect antidepressant target

Depression continues to grapple a large proportion of the population. Given the side effects associated with the long-term use of conventional antidepressants, there is a need for novel rapid acting therapeutics with minimal side effects. Researchers h…

AI innovation unlocks non-surgical way to detect brain cancer spread

Researchers have developed an artificial intelligence (AI) model to detect the spread of metastatic brain cancer using MRI scans, offering insights into patients’ cancer without aggressive surgery.

Global study pinpoints genes for depression across ethnicities

New genetic risk factors for depression have been identified across all major global populations for the first time, allowing scientists to predict risk of depression regardless of ethnicity. The world’s largest and most diverse genetic study ever into…

Brain connectome phenotype linked to cerebrovascular disease can track cognitive decline

Researchers have uncovered novel insights into how brain function disruptions related to cerebrovascular disease (CeVD) interact with Alzheimer’s disease (AD) pathology to impact neurodegeneration and cognition in older adults.

Route of entry for Semliki Forest virus into the brain revealed

Semliki Forest virus was originally isolated from mosquitoes in the Semliki Forest, Uganda, hence the name. Upon systemic infection from mosquito bites, Semliki Forest virus causes mild blood viremia before finding its way to the central nervous system…

Men more than three times as likely to die from a brain injury

An analysis of U.S. mortality data reveals the disproportionate impact of traumatic brain injuries (TBI) on older adults, males and certain racial and ethnic groups.

High levels of disordered eating among young people linked to brain differences

More than half of 23-year-olds in a European study show restrictive, emotional or uncontrolled eating behaviors, according to new research. Structural brain differences appear to play a role in the development of these eating habits.

Study advances possible blood test for early-stage Alzheimer’s disease

Declining blood levels of two molecules that occur naturally in the body track closely with worsening Alzheimer’s disease, particularly in women. Levels were found to drop gradually, from women with no signs of memory, disorientation, and slowed thinki…

How deep sleep clears a mouse’s mind, literally

A good night’s sleep does more than just help you feel rested–it might literally clear your mind. A new study shows how deep sleep may wash away waste buildup in the brain during waking hours, an essential process for maintaining brain health. The fin…

Researchers unravel a novel mechanism regulating gene expression in the brain that could guide solutions to circadian and other disorders

A collaborative effort has shed valuable light on how monoamine neurotransmitters such as serotonin, dopamine, and now histamine help regulate brain physiology and behavior through chemical bonding of these monoamines to histone proteins, the core DNA-…