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Potential new biomarker for psychosis diagnosis

The current standard of care for psychosis is a diagnostic interview, but what if it could be diagnosed before the first symptom emerged? Researchers are pointing toward a potential biomarker in the brain that could lead to more timely interventions an…

Dopamine and serotonin work in opposition to shape learning

Research shows that reward-based learning requires the two neuromodulators to balance one another’s influence — like the accelerator and brakes on a car

Innovative approach maps gene activity in the living human brain

A groundbreaking method to profile gene activity in the living human brain has been developed. This innovative approach opens new avenues for understanding and treating neurological conditions like epilepsy.

Study reveals new way to unlock blood-brain barrier, potentially opening doors to treat brain and nerve diseases

Researchers developed an innovative approach — demonstrated in mouse models and isolated human brain tissue — to safely and effectively deliver therapeutics into the brain, providing new possibilities for treating a wide range of neurological and psy…

Brain shrinkage associated with Alzheimer’s therapies shows effectiveness rather than harm

A loss of brain volume associated with new immunotherapies for Alzheimer’s disease may be caused by the removal of amyloid plaques, rather than the loss of neurons or brain tissue, finds a new study.

Overthinking what you said? It’s your ‘lizard brain’ talking to newer, advanced parts of your brain

Scientists sought to better understand how humans evolved to become so skilled at thinking about what’s happening in other peoples’ minds. The findings could have implications for one day treating psychiatric conditions such as anxiety and depression.

New insights into sleep uncover key mechanisms related to cognitive function

While it’s well known that sleep enhances cognitive performance, the underlying neural mechanisms, particularly those related to nonrapid eye movement (NREM) sleep, remain largely unexplored. A new study has nonetheless uncovered a key mechanism by whi…

Smarter city planning: Researchers use brain activity to predict visits to urban areas

Researchers have measured the brain activity of people who had never been to a specific city and then use this brain activity to predict other people’s actual visits to places around that city. This offers potential applications for urban planning and …

New imaging method enables detailed RNA analysis of the whole brain

Researchers have developed a groundbreaking microscopy method that enables detailed three-dimensional (3D) RNA analysis at cellular resolution in whole intact mouse brains. The new method, called TRISCO, has the potential to transform our understanding…

Signals of inflammation during pregnancy linked to aging and memory changes 50 years later

A new study analyzed data from participants who have been followed for over 50 years, starting before their births. Researchers found that maternal immune activity during a critical period of sex-dependent brain development in pregnancy affected the of…