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‘Smooth brain’ disorders may share a common cause  —  and potential treatment

Lissencephaly is a spectrum of rare, genetic disorders in which the brain fails to develop its hallmark folds. The disorders are often associated with seizures and intellectual disability and currently there are no available treatments. A new study, ho…

Study reveals that sleep prevents unwanted memories from intruding

The link between poor sleep and mental health problems could be related to deficits in brain regions that keep unwanted thoughts out of mind.

Herpes virus might drive Alzheimer’s pathology

Viral infections may play a role in Alzheimer’s disease.

Key players in brain aging: New research identifies age-related damage on a cellular level

Scientists have identified the molecular changes that occur in the brains of aging mice and located a hot spot where much of that damage is centralized. The cells in the area are also connected with metabolism, suggesting a connection between diet and …

Brain structure differences are associated with early use of substances among adolescents

A study of nearly 10,000 adolescents has identified distinct differences in the brain structures of those who used substances before age 15 compared to those who did not. Many of these structural brain differences appeared to exist in childhood before …

Propranolol reduces tremors in Parkinson’s disease

The standard medication levodopa does not always work against tremors in Parkinson’s disease, especially in stressful situations. Propranolol, however, does work during stress, providing insight into the role of the stress system in tremors. MRI scans …

New research identifies key cellular mechanism driving Alzheimer’s disease

Researchers have unveiled a critical mechanism that links cellular stress in the brain to the progression of Alzheimer’s disease (AD). The study highlights microglia, the brain’s primary immune cells, as central players in both the protective and harmf…

Brain map clarifies neuronal connectivity behind motor function

Scientists traced connectivity between neurons to identify how the brain communicates with the spinal cord to control motor function.

Poor vascular health accelerates brain aging

Using an AI tool, researchers have analyzed brain images from 70-year-olds and estimated their brains’ biological age. They found that factors detrimental to vascular health, such as inflammation and high glucose levels, are associated with an older-lo…

Integrating GABA and dopamine signals to regulate meal initiation

When you are feeling hungry, the brain takes the necessary steps toward consuming a meal. Many of these steps are not well known, but a new study reveals brain circuits and chemical messengers that contribute to the regulation of meal initiation and fo…