Little research has examined mean-level change in values across the life span. Using large cross-sectional data (N = 36,845) from the five geo-social regions in Brazil, this study examines how mean levels of basic values differ as a function of age (from age 12 to 65; M = 28) and whether age effects are moderated by gender. Results show that mean-level value change is substantial throughout the life course. We observed both linear and curvilinear patterns of change as well as differential patterns by gender. The observed value change is consistent with age-related life circumstances and psychosocial development. Age effects are also value dependent, supporting the notion that values have different functions for different developmental stages.