A new experimental study carried out in mice shows that microglia, immune cells of the brain, might play a key role in protecting the brain from Alzheimer’s disease (AD). It is long believed that toxic sticky protein deposits in the brain called amyloid beta (Aβ) are responsible for loss of memory in AD patients. Earlier studies have shown that microglia can remove Aβ protein from the brain and therefore be vital for successful therapy. New research indicates that microglia may play a significant role irrespective of their capacity to remove brain Aβ deposits.